We are currently recruiting subjects for a number of studies.  For more information on how to get involved with our research, please call 617-525-9896 or email the clinical research coordinators at jrussell0@bwh.harvard.edu or mnolan15@bwh.harvard.edu

Treating Hot Flash-Related Insomnia  (DORA)

Who: Healthy women ages 40-65 with hot flashes and sleep disturbance

What: Clinical research trial looking at suvorexant for the treatment of hot-flash related insomnia. Study participation includes 4 visits, 1-2 hours each, and taking a pill daily for 4 weeks

Where: Brigham and Women’s Hospital, Boston MA

If interested, please email or call: DORAtrial@bwh.harvard.edu; 617-525-6459

Participants may be compensated up to $275 for their time.

Study on Sleep, Hormones, and Diet (DAISY)

Who: Healthy women ages 21-45 who are not taking hormonal medications

What:  Clinical research study on hot flashes, sleep, and body fat gain. Study involves two inpatient stays (5 nights each) and four outpatient visits.

Where: Brigham and Women’s Hospital, Boston MA

If interested, please email or call:  DAISY@bwh.harvard.edu; 617-525-9896

Participants may be compensated up to $5,000 for their time.

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Study of Fatigue In Patients on Palbociclib   (SOFI-P)

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Who: Women with metastatic breast cancer who are starting palbociclib combination therapy as part of their breast cancer treatment

What: An observational study to examine the development and course of fatigue on treatment. No additional medication is given. Study includes 1 week of sleep and activity monitoring before treatment is started, and monthly follow-up during medication treatment (total time: approx. 7 months).

Where: Dana Farber Cancer Institute and Brigham and Women's Hospital, Boston MA. All study procedures can be completed remotely.

If interested, please email or call: SOFIresearch@bwh.harvard.edu; 617-732-5935

Participants may be compensated up to $315 for their time.

Hormone Therapies:

Who: Women who are starting tamoxifen or aromatase inhibitors as part of their breast cancer treatment.

What: An observational study to examine effects of hormone therapies on quality of life. Study participation includes completing surveys four times over 7 months and brief daily hot flash diaries for the first 8 weeks on hormone therapies. The study does not involve taking additional medication nor attending any in-person visits. Optional additional tasks include wearing a sleep monitor on your wrist for one week at 3 time points.

Where: Dana Farber Cancer Institute and Brigham and Women's Hospital, Boston MA. All study procedures can be completed remotely.

If interested, please email or call:  jrussell0@bwh.harvard.edu; 617-525-9896

Participants may be compensated up to $90 for their time.